胸部肿瘤内一科室主任 主任医师/教授 擅长胸部肿瘤，特别是在肺癌、胸膜间皮瘤及胸腺肿瘤的临床诊断、治疗与科研工作，并形成系统工作思路与体系；关注MDT诊疗模式，专注个体化综合治疗，尤其关注老年肺癌，兼顾治疗安全与生存获益，为高龄患者制定个体化方案。 转化研究聚焦肿瘤微环境，创新提出“微生物-肿瘤代谢偶联”理论，系统揭示肺腺癌相关菌群经乳酸-MCT1轴激活HIF-1α通路的机制，为靶向微环境提供新思路。 作为《CSCO非小细胞肺癌诊疗指南》专家组成员及《CACA老年肺癌保护指南》副主编，参与制定多项行业规范。主编《老年肺癌综合治疗学》，已成为该领域重要参考书。发表文章： · Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma. Cell Host & Microbe .2025; 33, 1089–1105. · Prognostic significance of micropapillary pattern and risk factors in patients with resected stage I lung adenocarcinoma and possible benefit of adjuvant therapy: a real-world multicenter study. Transl Lung Cancer Res 2025; 14(7):2760-2770 · Secreted proteins MDK, WFDC2, and CXCL14 as candidate biomarkers for early diagnosis of lung adenocarcinoma. BMC Cancer. 2023; 23:110 · Significant Upregulation of HERV-K (HML-2) Transcription Levels in Human Lung Cancer and Cancer Cells. Frontiers in Microbiology. March 2022 | Volume 13 | Article 850444 · Identification of serum biomarkers to predict pemetrexed/platinum chemotherapy efficacy for advanced lung adenocarcinoma patients by data-independent acquisition (DIA) mass spectrometry analysis with parallel reaction monitoring (PRM) verification. Transl Lung Cancer Res 2021;10(2):981-994