Work Experience Graduated from Peking University Health Science Center with a Doctor of Medicine degree. Since 2010, has been working in the Department of Endocrinology at Peking University Third Hospital, successively holding the positions of Resident Physician, Attending Physician, Associate Chief Physician and Associate Professor, and Chief Physician. In 2018, pursued advanced studies at the Joslin Diabetes Center at Harvard University in the United States, and in 2024, received training at the University of Michigan Medical Center. Since 2020, has served as the Party Branch Secretary of the Department of Endocrinology at Peking University Third Hospital, and since 2022, has served as the Deputy Director of the Department of Endocrinology at Peking University Third Hospital. Clinical work specializes in the diagnosis and treatment of diabetes, prediabetes, metabolic disease-related obesity, and thyroid diseases. Research Work Primary research interests focus on the pathogenesis of diabetes and its complications, as well as clinical research on comprehensive diabetes management. As the principal investigator, has led a total of 12 national and provincial/ministerial-level projects, including 4 projects funded by the National Natural Science Foundation of China, 1 project funded by the Beijing Municipal Natural Science Foundation, and 2 projects funded by the Beijing Municipal Health Commission (the Capital Health Development Research Project and the Research Ward Excellent Clinical Research Program Project), among others. Awards and Honors: Candidate for Academic Leader Reserve at Peking University Third Hospital Outstanding Teacher at Peking University Third Hospital Outstanding Communist Party Member at Peking University Third Hospital Third Prize of Beijing Municipal Science and Technology Award Outstanding Resident Physician at Peking University Health Science Center Publications: (1) Lin XF#, Cui XN#, Yang J#, Jiang YF, Wei TJ, Xia L, Liao XY, Li F, Wang DD, Li J, Wu Q, Yin DS, Le YY, Yang K, Wei R*, Hong TP*. SGLT2 inhibitors ameliorate NAFLD in mice via downregulating PFKFB3, suppressing glycolysis and modulating macrophage polarization. Acta Pharmacol Sin. 2024,45(12):2579-2597. (2) Jiang Y#, Yang J#, Xia L#, Wei T, Cui X, Wang D, Jin Z, Lin X, Li F, Yang K, Lang S, Liu Y, Hang J, Zhang Z*, Hong T*, Wei R*. Gut microbiota-tryptophan metabolism-GLP-1 axis participates in β-cell regeneration induced by dapagliflozin. Diabetes. 2024, 73(6):926-940. (3) Le Y, Zhang J, Hong T, Yang J*. Coexistence of type 2 diabetes mellitus, arginine vasopressin deficiency, and Marfan syndrome: A case report. J Diabetes Investig. 2024, 15(7):964-967. (4) Yang J, Wei R*. The future is on the way: β cell function preservation for type 1 diabetes. Med. 2024, 5(1):4-6. (5) Le Y#, Yang J#, Li F, Jiang Y, Wei T, Wang D, Wang K, Cui X, Lin X, Yang K, Hong T*, Wei R*. Dapagliflozin improves pancreatic islet function by attenuating microvascular endothelial dysfunction in type 2 diabetes. Diabetes Metab Res Rev. 2023, 39(3):e3607. (6) Yang J#, Le Y#, Wei T, Wang K, Yang K, Xiao W, Hong T*, Wei R*. Non-targeted metabolomic analysis predicts the therapeutic effects of exenatide on endothelial injury in patients with type 2 diabetes. J Diabetes Complications. 2021, 35(2):107797. (7) Yang J#, Tian Q#, Tang Y, Shah AK, Zhang R, Chen G, Zhang Y, Rajpathak S*, Hong T. Effect of dipeptidyl peptidase 4 inhibitors used in combination with insulin treatment in patients with type 2 diabetes: a systematic review and meta-analysis. Diabetes Ther. 2020, 11(10):2371-2382. (8) Yang J#, Xiao W#, Guo L, Li Q, Zhong L, Yang J, Yang J, Gao Y, Tian Q, Hong T*. Efficacy and safety of generic exenatide injection in Chinese patients with type 2 diabetes: a multicenter, randomized, controlled, non-inferiority trial. Acta Diabetol. 2020, 57(8):991-1000. (9) Yang J#, Zhang Z#, Zhang L, Su Y, Sun Y*, Wang Q*. Relationship between self-care behavior and cognitive function in hospitalized adult patients with type 2 diabetes: a cross-sectional study. Diabetes Metab Syndr Obes. 2020, 13:207-214. (10) Liu G#, Yang K#, Le Y, Wei R, Hong T*, Yang J*. High Vitamin D Level in Female Mice Increases the Number of Live Fetuses. J Nutr Sci Vitaminol (Tokyo). 2023, 69(1):1-6. (11) Yang K, Wang H, Wei R, Xiao W, Tian Q, Wang C, Yang J*, Hong T*. High baseline FGF21 levels are associated with poor glucose-lowering efficacy of exenatide in patients with type 2 diabetes. Acta Diabetol. 2021, 58(5):595-602. Books and Translations "Excellent Cases of Chronic Disease Management Practice in Beijing", Peking Union Medical College Press, June 2025, Editorial Board Member Clinical Thinking Training Series for Residents - "Internal Medicine", Peking University Medical Press, February 2025, Editorial Board Member Endocrine Case Analysis Series - "Diabetes Case Analysis", Shanghai Scientific and Technological Literature Press, January 2025, Deputy Editor-in-Chief "Prehabilitation for Cancer Surgery", Higher Education Press, January 2025, Translator "Internal Medicine", Peking University Medical Press, October 2023, Editorial Board Member "Clinical Endocrinology" Second Edition, Shanghai Scientific and Technological Literature Press, August 2022, Editorial Board Member "Caring for the Vital Gland - Know Early About Thyroid Issues", Chemical Industry Press, November 2024, Editorial Board Member "As Physicians Say", Peking University Medical Press, July 2024, Editorial Board Member "The Complete Guide to Managing Diabetes with Ease", Chemical Industry Press, January 2017, Editorial Board Member