Chief Physician, Doctoral Supervisor, Academic Leader of Anesthesiology. He has been engaged in clinical anesthesiology for more than 30 years. He studied organ transplant anesthesia, pharmacokinetic-pharmacodynamic modeling and developmental pharmacology at the University of Pittsburgh Medical Center (UPMC) and Cincinnati Children's Hospital Medical Center (CCHMC). He has won the Third Prize of Shanghai Science and Technology Progress Award, the Third Prize of Shanghai Medical Science and Technology Progress Award, and the Third Prize of Hubei Science and Technology Progress Award. His main research directions: developmental anesthetic pharmacology, development and pain.
Research projects obtained in recent years (past five years, top three principal investigators)
1. Mechanism study of microglia-mediated neonatal pain "memory" (82371289), National Natural Science Foundation of China
2. Study on the mechanism of LncRNA Silc1 regulating Elavl4/GAP43 to induce adolescent delayed neuropathic pain (20ZR1434600)
3. Pediatric Anesthesiology (2015ZB0106), Key Weak Discipline Construction Project of Shanghai Health and Family Planning Commission
4. Development of a hybrid physiologically based pharmacokinetic-pharmacodynamic model with propofol as a tool drug based on single-ventricle circulation (81270414), National Natural Science Foundation of China
5. Population pharmacokinetics of etomidate and remifentanil under TGA disease state and the effects of drug-drug interaction on systemic and pulmonary vascular resistance and cerebral oxygen extraction rate (81202597), National Natural Science Foundation of China
6. Analysis of pharmacokinetic-pharmacodynamic models of propofol and remifentanil based on Bayesian estimation and generalized additive model and construction of response surface model for their pharmacodynamic interaction (30972841), National Natural Science Foundation of China
7. Study on pharmacodynamics, pharmacokinetics and metabolic enzymes of target-controlled infusion of propofol in obstructive jaundice (30901394), National Natural Science Foundation of China
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