Education and Work Experience He pursued his master’s degree in Orthopedics at Sun Yat-sen University of Medical Sciences in 1985 and his doctoral degree in 1991.

Research Interests Functional mechanisms of osteosarcoma stem cells and pulmonary metastasis. He has published 78 SCI-indexed papers, 59 of which were published as first or corresponding author, with a total impact factor of 286.177. His representative works have appeared in leading oncology journals including Nature Cell Biology, Journal of the National Cancer Institute, Journal of Clinical Investigation and Clinical Cancer Research. His basic and translational research on the pathogenesis and metastatic mechanisms of osteosarcoma is at the leading level in China. He is among the first batch of Famous Physicians of Sun Yat-sen University, listed in the Top 100 Chinese Physicians, and has been awarded the National Distinguished Physician Award for Outstanding Achievements, Guangdong Physician Award and Guangdong Outstanding Teacher Award. The academic talents he has trained have obtained 1 project of the Ministry of Education Postdoctoral Innovative Talent Support Program, 1 key project and 3 training projects for young teachers of Sun Yat-sen University, and 2 outstanding talent programs of this hospital. He has established sound collaborative relationships with multiple overseas bone tumor centers, including Memorial Sloan Kettering Cancer Center in New York, Mayo Clinic, Shands Hospital, MD Anderson Cancer Center, the Rizzoli Orthopaedic Institute in Italy, University Health Network in Toronto, Canada, as well as the State Key Laboratory of Oncology in South China and various on-campus laboratories of Sun Yat-sen University.

Clinical Expertise: (1) Preoperative needle biopsy for the diagnosis of bone tumors; (2) Challenging major operations including limb-salvage surgery for various malignant bone and soft tissue tumors, limb salvage and expandable prosthesis techniques for pediatric bone tumors, and resection and reconstruction of pelvic and spinal tumors; (3) Orthopedic correction of skeletal deformities; repair and reconstruction of large osteoarticular defects; management of bone diseases and osteomyelitis; (4) Adjuvant chemotherapy, intraoperative radiotherapy, targeted therapy, immunotherapy and other biological treatments for malignant bone tumors.