He graduated from the five-year Clinical Medicine Program of Xiangya School of Medicine, Central South University in 2007, and later obtained his Master of Medicine degree at The First Affiliated Hospital of Sun Yat-sen University. He has been working in the Department of Pediatric Surgery of this hospital ever since graduation and was awarded his Doctor of Medicine degree by Sun Yat-sen University in 2021.
Research: He has published more than 10 SCI papers as first author, corresponding author or co-corresponding author in high-impact international journals including Cell Reports Medicine, Frontiers in Pediatrics, Pediatr Surg Int and Int J Hyperthermia. He has delivered keynote presentations at the Annual Congress of Chinese Pediatric Surgery and the Annual Conference on Pediatric Oncology for multiple times. He participated in compiling Pediatric Abdominal Surgery (2nd Edition).
Research Interests: Diagnosis and treatment of pediatric hepatobiliary and pancreatic malignancies as well as mechanisms underlying their recurrence and metastasis. Major achievements are as follows: 1. First evaluated the prognostic predictive value of international staging systems for Chinese pediatric patients, reflecting the current diagnosis and treatment status of hepatoblastoma in South China. 2. First explored the efficacy of irreversible electroporation and radiofrequency ablation for recurrent hepatoblastoma to provide additional therapeutic options for affected children. 3. First characterized the immune microenvironment of hepatoblastoma at the single-cell level, offering potential targets and novel strategies for immunotherapy. 4. Uncovered the epigenomic signatures of primary and recurrent hepatoblastoma to support research on individualized precision therapy.
Clinical Expertise: Surgical management of pediatric solid tumors involving the liver, biliary tract, pancreas, spleen, kidney, adrenal gland and gonads, with special focus on hepatoblastoma, nephroblastoma, neuroblastoma and germ cell tumors. He has rich experience in congenital pediatric hepatobiliary disorders including biliary atresia, choledochal cyst and cavernous transformation of the portal vein, as well as congenital gastrointestinal obstruction and malformations in fetuses and neonates. He also has successful experience in treating rare pediatric solid tumors and complicated refractory conditions.
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