The Department of Minimally Invasive Oncology at Peking University International Hospital is a clinical discipline established under the guidance of Professor Zheng Jiasheng, a renowned expert in minimally invasive oncology, based on the "Dual-Minimally Invasive Theory." It integrates medicine, education, research, prevention, and the coordinated development of traditional Chinese and Western medicine. The department advocates a new model of tumor minimally invasive scarless treatment featuring early screening, early diagnosis, and early treatment (the "Three Earlies") of tumors, particularly early-stage minimally invasive treatment, as well as preservation of anatomical structure, physiological function, and immune function (the "Three Preservations"). The department utilizes minimally invasive procedures such as transarterial chemoembolization, yttrium-90 local radioembolization, sequential CT-, MRI-, DSA-, ultrasound-, and endoscopy-guided tumor nano-knife ablation, cryoablation, microwave ablation, radiofrequency ablation, laser ablation, chemical ablation, photodynamic therapy, and I125 radioactive seed implantation to precisely eliminate imaging-visible liver cancer, lung cancer, pancreatic cancer, renal cancer, oligometastatic cancer, prostate cancer, breast cancer, thyroid cancer, bone metastases, mediastinal tumors, and retroperitoneal tumors. Combined with holistic microenvironment regulation through traditional Chinese medicine, targeted drugs, immunotherapy, and cell therapy, it remodels the body's immune microenvironment to eliminate imaging-invisible micrometastases. Precise minimally invasive surgery removes tumors and blocks cancer pain. Precise scarless minimally invasive radical ablation surgery treats pulmonary nodules, thyroid nodules, breast nodules, hepatic hemangiomas, hepatic cysts, renal cysts, and benign prostatic hyperplasia. Minimally invasive surgery reverses liver cirrhosis and blocks the progression from hepatitis to liver cirrhosis to liver cancer. The Department of Minimally Invasive Oncology is fully committed to advancing the new tumor prevention and treatment model of the "Three Earlies" and the "Three Preservations," creating a new humanistic diagnostic and therapeutic paradigm of "minimally invasive, scarless healing."